Mark J Graham Selected Research

2-acylglycerol O-acyltransferase

1/2021	Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis.
10/2014	Inhibiting monoacylglycerol acyltransferase 1 ameliorates hepatic metabolic abnormalities but not inflammation and injury in mice.
7/2014	Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice.

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Mark J Graham Research Topics

Disease

19	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 05/2005
13	Obesity 01/2021 - 12/2006
13	Insulin Resistance 01/2021 - 12/2006
12	Atherosclerosis 11/2019 - 02/2006
10	Inflammation (Inflammations) 01/2021 - 03/2005
9	Non-alcoholic Fatty Liver Disease 01/2021 - 05/2007
6	Type 2 Diabetes Mellitus (MODY) 01/2021 - 06/2012
6	Hypertriglyceridemia 01/2021 - 12/2006
6	Fatty Liver 01/2017 - 10/2008
5	Hypercholesterolemia 01/2022 - 08/2006
5	Fibrosis (Cirrhosis) 10/2019 - 02/2009
4	Hyperlipidemias (Hyperlipidemia) 01/2021 - 05/2005
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 05/2011
4	Body Weight (Weight, Body) 02/2016 - 04/2012
3	Hypertension (High Blood Pressure) 01/2021 - 01/2017
3	Hyperglycemia 01/2021 - 12/2014
3	Aortic Valve Stenosis (Aortic Stenosis) 11/2016 - 10/2015
3	Myocardial Infarction 11/2016 - 01/2014
3	Dyslipidemias (Dyslipidemia) 08/2016 - 12/2006
3	Liver Diseases (Liver Disease) 09/2010 - 05/2008
3	Hepatomegaly 09/2010 - 05/2008
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 11/2019
2	Hepatitis 10/2019 - 01/2017
2	Acute Kidney Injury (Acute Renal Failure) 10/2018 - 01/2017
2	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 07/2015
2	Pancreatitis 07/2015 - 12/2014
2	Weight Gain 10/2014 - 11/2010
2	Pain (Aches) 03/2010 - 12/2008
1	Reperfusion Injury 01/2021
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2021
1	Ischemia 01/2021
1	Alcoholic Fatty Liver 10/2019
1	Liver Cirrhosis (Hepatic Cirrhosis) 10/2019
1	Chronic Renal Insufficiency 10/2018
1	Overnutrition 01/2018

Drug/Important Bio-Agent (IBA)

25	Antisense OligonucleotidesIBA 01/2021 - 03/2005
17	Triglycerides (Triacylglycerol)IBA 01/2021 - 12/2006
14	CholesterolIBA 01/2022 - 05/2008
14	LipidsIBA 01/2022 - 05/2007
12	Insulin (Novolin)FDA Link 01/2022 - 12/2006
9	LDL Receptors (LDL Receptor)IBA 01/2021 - 08/2006
8	Messenger RNA (mRNA)IBA 01/2018 - 03/2005
8	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 05/2007
7	ApolipoproteinsIBA 01/2021 - 05/2005
6	Apolipoprotein C-IIIIBA 01/2021 - 05/2013
6	EnzymesIBA 01/2021 - 05/2008
6	Lipoproteins (Lipoprotein)IBA 11/2019 - 08/2006
5	DiglyceridesIBA 01/2021 - 11/2010
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2007
4	LDL CholesterolIBA 01/2022 - 01/2014
4	dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)IBA 01/2017 - 01/2015
4	trimethyloxamine (trimethylamine N-oxide)IBA 01/2017 - 01/2015
4	Apolipoproteins B (ApoB)IBA 05/2011 - 05/2005
3	2-acylglycerol O-acyltransferaseIBA 01/2021 - 07/2014
3	oxidized low density lipoproteinIBA 01/2018 - 05/2005
3	Angiotensin IIIBA 01/2017 - 01/2016
3	Lipoprotein(a)IBA 11/2016 - 10/2015
3	Pharmaceutical PreparationsIBA 03/2016 - 05/2005
3	C-Reactive ProteinIBA 01/2014 - 11/2012
3	Perilipin-2IBA 11/2012 - 05/2007
2	VLDL LipoproteinsIBA 01/2021 - 01/2017
2	MonoglyceridesIBA 01/2021 - 07/2014
2	AcyltransferasesIBA 10/2019 - 08/2006
2	AngiotensinogenIBA 01/2019 - 01/2017
2	OligonucleotidesIBA 01/2018 - 01/2017
2	AcidsIBA 01/2017 - 10/2008
2	O(4)-methylthymidine triphosphateIBA 01/2017 - 03/2014
2	Carrier Proteins (Binding Protein)IBA 01/2017 - 10/2008
2	microsomal triglyceride transfer proteinIBA 01/2017 - 03/2014
2	ISIS 304801IBA 08/2016 - 12/2014
2	ISIS-APO(a)RxIBA 03/2016 - 10/2015
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2016 - 03/2014
2	Proprotein Convertase 9IBA 01/2016 - 07/2015
2	Acyl Coenzyme A (Acyl CoA)IBA 12/2014 - 08/2006
2	Oxidoreductases (Dehydrogenase)IBA 06/2012 - 05/2011
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2012 - 05/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2010 - 02/2009
2	GlycosphingolipidsIBA 09/2010 - 05/2008
2	Analgesics (Analgesic Drugs)IBA 03/2010 - 12/2008
2	Sterol O-AcyltransferaseIBA 04/2008 - 08/2006
1	Ezetimibe (Zetia)FDA Link 01/2022
1	Bile Acids and Salts (Bile Acids)IBA 01/2022
1	Steroid 12-alpha-Hydroxylase (CYP8B1)IBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022
1	Simvastatin (Zocor)FDA LinkGeneric 01/2022
1	Insulin ReceptorIBA 01/2022
1	LeptinIBA 01/2021
1	AngiotensinsIBA 01/2019
1	ReninIBA 01/2019
1	Low Density Lipoprotein Receptor-Related Protein-2IBA 01/2019
1	acetoacetic acid (acetoacetate)IBA 01/2019
1	OsteopontinIBA 11/2018
1	RNA (Ribonucleic Acid)IBA 10/2018
1	Phosphates (Orthophosphate)IBA 01/2018
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2018
1	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 01/2017

Therapy/Procedure

7	Therapeutics 01/2021 - 10/2013
1	Glycemic Control 01/2022
1	Liver Transplantation 01/2021
1	Drug Therapy (Chemotherapy) 11/2018